Presynaptic neuromuscular transmission defect in the stiff person syndrome
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چکیده
منابع مشابه
Presynaptic neuromuscular transmission defect in the stiff person syndrome
BACKGROUND The stiff person syndrome (SPS) is a rare disorder characterized by muscular rigidity and stiffness. CASE PRESENTATIONS We describe an SPS patient presenting with longstanding fatigue and electrophysiological evidence of presynaptic neuromuscular transmission defect, who responded to administration of pyridostigmine. In contrast, no electrophysiolgical evidence of neuromuscular tra...
متن کاملStiff eyes in stiff-person syndrome.
since 1951, it is now a weekly with 48 issues per year.
متن کاملStiff Person Syndrome.
Stiff-person syndrome or Moersch-Woltmann is a very rare and disabling neurologic disorder characterized by muscle rigidity and episodic spasms involving axial and limb musculature. It is an autoimmune disorder resulting in a malfunction of aminobutyric acid mediated inhibitory networks in the central nervous system. We describe a patient of stiff person syndrome.
متن کاملStiff person syndrome.
Recognizing stiff person syndrome is clinically important. It is uncommon, characterized by body stiffness associated with painful muscle spasms, and varies in location and severity. It is subdivided into stiff trunk versus stiff limb presentation, and as a progressive encephalomyelitis. Stiff person-type syndrome also reflects a paraneoplastic picture. Most patients demonstrate exaggerated lum...
متن کاملStiff-person syndrome.
The stiff-person syndrome is a disorder of persistent, painful muscle contractions predominately affecting the axial musculature. We describe a patient with this disorder and review its pathophysiology. Molecular biologic and immunologic techniques have recently added to the understanding of the mechanism of this disorder. Association with diseases such as diabetes, vitiligo and hypothyroidism ...
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ژورنال
عنوان ژورنال: BMC Neurology
سال: 2016
ISSN: 1471-2377
DOI: 10.1186/s12883-016-0773-2